CT-101; Covid 19 CT-101 inhibits efficiently virus replication at the post‐entry stages of the SARS‐CoV‐2 infection.Antiviral activity of CT-101 is highly potent antiviral drug.
CT-401; Rheumatoid arthritisThe conjugate of Cell Penetrating Peptide(CPP) and Disease-Modifying Antirheumatic Drug (DMARD) to enhance transdermal delivery of DMARD, particularly strong effect for minimize the toxicity of DMARD & lower dose and improve the usage.
CT-503; Anti-wrinkle agent Transdermal cosmetics for anti-wrinkle effect and its toxicity is much lower than that of Botox.26 AA. peptide generated by Botox E.Inhibition of neurotransmitter release by disrupting the vesicle fusion complex.
CT-1106; Ischemic heart diseaseMyocardial Ca2+ overload induced by ischemia/reperfusion (I/R) is a major element of myocardial dysfunction in heart failure. CT-1106 plays important roles in the regulation of the phosphoinositol pathway and Ca2+ homeostasis in various types of cells.
CT-ct4; ImmunosuppressantThe fusion protein between CPP and the cytoplasmic domain of CTLA-4 which is a negative regulator for T cell activation.Drugs that lower abnormal immune responses and are treated for autoimmune disease such as rheumatoid arthritis, psoriasis, asthma, atopic dermatitis, crohn’s disease.
CT-1206; Cytoprotection CT-1206 inhibits the apoptosis of adult stem cell by external stimuli such as hypoxia and reactive oxygen species, and improves survival rate of adult stem cell implanted in infarct zone. The operation of stem cell treated by CT-1206 is more efficient and safe than method using the DNA.
CT-2107; HCVsiRNA has a high specificity to target gene, and is expected to be main technology for biological drugs in next era.The surface charge of siRNA is negative, and the efficacy of penetration into cell is very low.
CT-2109; Allergic autoimmune diseaseRegulation of Regulatory T(Treg) cells development and function.Transcriptional repressor (associates with NFATc2, NF-kB, AML1/Runx1, …) → suppression of the cytokine gene expression.Upregulation of the immunosuppressive gene expression.
CT-2301; Atopy(Vp8N) Inhibition of histamine release through SNARE complex inhibition of mast cell.
CT-Lex; Atopy(Lex) SNARE4 (Syntaxin4, SNAP-23, VAMP2 or VAMP8) is responsible for the extracellular secretion of granules containing allergy-inducing substances such as histamine in mast cells. CT-Lex can inhibit atopy by inhibiting the formation of the SNARE4 complex.
CT-101; Covid 19
CT-101 inhibits efficiently virus replication at the post‐entry stages of the SARS‐CoV‐2 infection.
Antiviral activity of CT-101 is highly potent antiviral drug.
CT-401; Rheumatoid arthritis
The conjugate of Cell Penetrating Peptide(CPP) and Disease-Modifying Antirheumatic Drug (DMARD) to enhance transdermal delivery of DMARD, particularly strong effect for minimize the toxicity of DMARD & lower dose and improve the usage.
CT-503; Anti-wrinkle agent
Transdermal cosmetics for anti-wrinkle effect and its toxicity is much lower than that of Botox.
26 AA. peptide generated by Botox E.
Inhibition of neurotransmitter release by disrupting the vesicle fusion complex.
CT-1106; Ischemic heart disease
Myocardial Ca2+ overload induced by ischemia/reperfusion (I/R) is a major element of myocardial dysfunction in heart failure.
CT-1106 plays important roles in the regulation of the phosphoinositol pathway and Ca2+ homeostasis in various types of cells.
CT-ct4; Immunosuppressant
The fusion protein between CPP and the cytoplasmic domain of CTLA-4 which is a negative regulator for T cell activation.
Drugs that lower abnormal immune responses and are treated for autoimmune disease such as rheumatoid arthritis, psoriasis, asthma, atopic dermatitis, crohn’s disease.
CT-1206; Cytoprotection
CT-1206 inhibits the apoptosis of adult stem cell by external stimuli such as hypoxia and reactive oxygen species, and improves survival rate of adult stem cell implanted in infarct zone.
The operation of stem cell treated by CT-1206 is more efficient and safe than method using the DNA.
CT-2109; Allergic autoimmune disease
Regulation of Regulatory T(Treg) cells development and function.
Transcriptional repressor (associates with NFATc2, NF-kB, AML1/Runx1, …) → suppression of the cytokine gene expression.
Upregulation of the immunosuppressive gene expression.
CT-2301; Atopy(Vp8N)
Inhibition of histamine release through SNARE complex inhibition of mast cell.
CT-Lex; Atopy(Lex)
SNARE4 (Syntaxin4, SNAP-23, VAMP2 or VAMP8) is responsible for the extracellular secretion of granules containing allergy-inducing substances such as histamine in mast cells.
CT-Lex can inhibit atopy by inhibiting the formation of the SNARE4 complex.
